CBD and the Liver



For those of you that have been closely following my blog you will already know that recently my ALP (alkaline phosphatase) test results were slightly elevated. If you haven’t read that post, you can click here.  Hi, CEO Olivia here, today I’m barking about CBD & the liver.

Back in March  2020 the FDA & the media were giving CBD some pawsitively negative coverage alleging that CBD raised liver enzymes.  The study they based this misinformation on involved a synthetic CBD isolate called Epidiolex. It’s made by a pharmaceutical company called GW Pharmaceuticals, who want to monopolize all medical cannabis medications. The dosages used in this study were pawsitively, dog gone, ridiculously high even for humans yet they were administered to mice. Also, because Epidiolex is synthetic, there were no other cannabinoids present, therefore there was no entourage effect.

But lets look at naturally derived CBD oil. Studies by the American National Institute of Health reported way back in 2013 that CBD had therapeutic potential for many diseases.

Time for a quick refresher, if you have a spine, you have a endocannabinoid system with cannabinoid receptors. There are two subtypes called CBD1 & you guessed it, CBD2.

In the liver & kidneys, if CBD1 receptors becomes overstimulated they weaken the CBD2 receptors, throwing both out of balance. This can lead to serious health issues. CBD1 is what’s called profibrotic which means it encourages fibrous connective tissue in response to an injury. CBD2 is the opposite, it’s antifibrotic meaning it impedes fibrosis & acts as a blood thinner. You can see how it’s impawtant that they work together in harmony.

Taking CBD from Cannabis/hemp has been shown to fine tune the CBD1 & CBD2 receptors & bring them back into balance if needed. Research suggests that taking CBD regularly can maintain this balance.

There have been published studies that have shown that CBD is beneficial to the liver & helps keep it healthy. In one study, when administered to rats who were intentionally given liver disease, the CBD killed off cells which cause scar tissue within the liver. Please note that we here at KTFGD’s are against using animals for lab testing.

Research is ongoing but time after time, results show that not only that there is no evidence of CBD oil causing damage to the liver, quite the opposite seems to be true. CBD appears to help maintain a healthy functioning liver.

I have continued taking my full spectrum CBD oil. I am going to dig deeper into that soon. huMom has observed no adverse affects & I’m 170 days seizure free today. If you haven’t, please sniff out my blog series exploring CBD, I walk you through from the plant in the field to the finished product. It’s benefits & how to avoid being sold ‘snake oil’ are also dogsplained. Here are the links:

Part 1 – CBDs, Cannabinoids, Endocannabinoids & Canines

Part 2 – What is Cannabis?

Part 3 – How CBD Is Extracted?

Part 4 – CBD Full Spectrum, Broad Spectrum & Isolates

Part 5 – CBD Oils & Tinctures, What’s In the Bottle?

Part 6 – Understanding a CBD Certificate of Analysis

Part 7 – CBD Oils, What Should Be On the Label?

Part 8 – CBD Micro Dosing Explained

Part 9 – CBD & the Liver

Have a pawsome week.

CEO Olivia

PS 🐾 Looking for wagnificent healthy & furbulously fun toys or pawsibly a supplement for the well being of your pawtacular good dog or cat? Shop Naturally

4 thoughts on “CBD and the Liver

    1. It is my understanding that although CBD is processed through the liver there is more scientific evidence that it is beneficial than harmful. Unlike phenobarbital which can be pawsitively harmful.
      When talking about elevated liver enzymes, let’s remember that many factors including eating, stress, mild infections etc..can cause temporary rise in liver enzymes.

      Liked by 1 person

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