Olivia’s Annual Checkup Part 3

News

Hello everyone. Today I’m barking about the follow up phone calls between my huMom & my vet Dr. Jodi. My huMom had lots of questions & Dr. Jodi was herself doing research on my behalf. Both wanted to plot the best way forward for yours truly.

We left off last week waiting to hear back from Dr. Jodi to discuss a schedule strategy for lowering my phenobarbital medication. When she called we were told that the best approach was to go as slow as possible.  A 25% reduction was the plan. What that would mean for me is that my 60mg dose every 12 hours would go to 45mg every 12 hours for a minimum of 4 weeks.  At the 2 week mark we would touch base & discuss how things were going.  If all goes well we would decrease my dose another 25% for an additional 4 weeks with another 2 week check in point. That would reduce my dose from 45mg to 30mg every 12 hours; half of the dose I currently take. From there 25% would take us to 22.5mg & that would be difficult to administer.  For that reason Dr. Jodi would have to look into other possible means of meeting a closer range, i.e. 20mg. I should bark that if we were to see breakthrough seizures we would have to readdress lowering the dose any further.

Since we were coming into a full moon cycle we decided to wait until after April 29th to begin this reduction; that is, as long as there was no unsettling weather.

During the wait for our projected start date Dr. Jodi called again.  She wanted to share some new information she had learned regarding Phenobarbital & ALP levels & the risk involved in decreasing phenobarbital to sub therapeutic levels especially for a Epilepsy Warrior like myself who experiences cluster seizures.

Dr. Jodi informed us that certain medications can turn on the production of ALP & phenobarbital happens to be one of those drugs.  Phenobarbital can benignly cause an elevated ALP (Alkaline phosphatase) but it can also cause liver damage. She felt that my ALP level was not of great concern at this point.

Dr. Jodi also shared her concerns around breakthrough seizures if we were to lower my dose of phenobarbital to sub therapeutic levels.  She had read that after reducing phenobarbital, if I were to have breakthrough seizures it could be difficult for me to regain management with this drug. With my history of cluster seizures she was concerned that this was a possibility.  HuMom & Dr. Jodi discussed quality of life & how seizure management is of the upmost importance.  Her recommendation is to stay at my current dose & retest in 2-3 months.

HuMom explained that I am currently using a CBD product that we feel is responsible for the increase in my seizure free days; today I am at 82 days.  HuMom went on to say she understood that CBD could increase the efficacy of AEDs (anti epileptic drugs) & that it was our hope when we started our CBD journey to reduce some of my AEDs; more so my phenobarbital. However, we were looking for a greater number of seizure free days; more like 6 months to a year before having this discussion.  With that said, huMom agreed to continue my dose at it’s current 60mg every 12 hours & we would recheck my ALP levels again July 13th.

There are many reason that a dog could have elevated ALP levels & I intend to do a blog post on this topic in the future.

I of course will also keep everyone pupdated about my next blood tests in July.

💜 nose nudges 💜

CEO Olivia

 

What is Cannabis?

News

Hello everyone, CEO Olivia here. Let’s begin our exploration of CBD, Cannabinoids & endocanabinoids at the beginning, out in the fields. What is Cannabis anyway?

Cannabis has been cultivated by humans for many thousands of years. There is evidence of it being grown in what is today the Czech Republic, dating back to 26,900 BCE. It can be used for making rope, clothing, paper, bricks & also dog toys. BOL! You can even use cannabis in 3D printing.

There are two main varieties of cannabis. One is called marijuana & the other is called hemp. Both contain chemical compounds known as cannabinoids. There are 113 cannabinoids in all. But the difference between the plants comes down to how much one specific cannabinoid is present. Tetrahydrocannabinol or THC is present in both plants, however, Marijuana will have  a THC concentration higher than 0.3%. If the plant has 0.3% or less of THC it is then classified as hemp. Both plants contain another cannabinoid called cannabidiol or CBD.

All mammals as well as several other animals (like fish) have what is called an endocannabinoid system. Endocannabinoids are neurotransmitters that are located throughout the central nervous system, including the brain. Research has shown these neurotransmitters help regulate appetite, pain, memory, mood/stress & sleep. It’s these endocannabinoid neurotransmitters that the cannabinoids found in cannabis bind to. I’ll dig deeper into this in a future post.

But first, next week I’ll sniff out the methods used to extract & process the cannabinoids from cannabis.

CEO Olivia

Part 1 – CBDs, Cannabinoids, Endocannabinoids & Canines

Part 2 – What is Cannabis?

Part 3 – How CBD Is Extracted?

Part 4 – CBD Full Spectrum, Broad Spectrum & Isolates

Part 5 – CBD Oils & Tinctures, What’s In the Bottle?

Part 6 – Understanding a CBD Certificate of Analysis

Part 7 – CBD Oils, What Should Be On the Label?

Part 8 – CBD Micro Dosing Explained

CBDs, Cannabinoids, Endocannabinoids & Canines

News

Hello everyone, CEO Olivia here. As my huMom & I sniff about the inter-webs, we see a lot of people asking about CBD oil use for their good dogs. A lot of “experts” seem to know a lot about it. But it’s a very complex subject.

Research into the medicinal benefits of cannabis & hemp products are still in the early stages due to these plants being illegal for decades. But it seems clear that there are many compounds that can help in regards to pain management, calmness & even help with seizures.

There is a lot of information out there, some good, some not so much. For the next few Monday’s, I’ll be barking about what is known about the potential benefits of Cannabis & hemp oils. As well we will be sniffing out what is an endocannabinoid and how does it pawtain to us canines.

Full disclosure, Knotty Toys for Good Dogs has an affiliate program with Charlotte’s Web CBD products but at present, I do not  take any CBD products. With that said, I have in the past & we are open to using it again when we feel more knowledgeable.  Of course we would discuss this with our Vet first.   All of this will be shared with you later in a future post.

So stay tuned for the next few Monday’s & I’ll sniff out facts from fiction.

CEO Olivia

Part 1 – CBDs, Cannabinoids, Endocannabinoids & Canines

Part 2 – What is Cannabis?

Part 3 – How CBD Is Extracted?

Part 4 – CBD Full Spectrum, Broad Spectrum & Isolates

Part 5 – CBD Oils & Tinctures, What’s In the Bottle?

Part 6 – Understanding a CBD Certificate of Analysis

Part 7 – CBD Oils, What Should Be On the Label?

Part 8 – CBD Micro Dosing Explained